Research
The FDA’s Guidance on Adaptive Design is Clear.
Access our fundamental researches and applications on innovative trial design, dynamic data monitoring, machine learning and AI technology for future clinical trials
Statistical Monitoring of Clinical Trials
K. K. Gordon Lan, Michael A. Proschan and Janet Wittes
Methods for flexible sample-size design in clinical trials: Likelihood, weighted, dual test, and promising zone approaches
Shih WJ, Li G, Wang Y (2016)
Data Monitoring for the Chinese Clinical Trials of Remdesivir in Treating Patients with COVID‑19 During the Pandemic Crisis
Shih WJ, Yao C, Xie T (2020)
Remdesivir is Effective for Moderately Severe Patients: A Re-Analysis of the First Double-Blind, Placebo-Controlled, Randomized Trial on Remdesivir for Treatment of Severe COVID-19 Patients Conducted in Wuhan City
Weichung J. Shih1, Xin Shen, Peng Zhang, Tai Xie (2020)
Dynamic Monitoring of On-Going Clinical Trials
Tai Xie, Peng Zhang, Weichung Joe Shih, Yue Tu, K.K. Gordon Lan
(submitted manuscript, 2020)
